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A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation

The Ovarian Carcinoma Immunoreactive Antigen domain (OCIAD) - containing proteins OCIAD1/Asrij and OCIAD2, are implicated in several cancers and neurodegenerative diseases. While Asrij has a conserved role in facilitating STAT3 activation for JAK/STAT signaling, the expression and function of OCIAD2...

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Detalles Bibliográficos
Autores principales: Sinha, Saloni, Bheemsetty, Venkata Anudeep, Inamdar, Maneesha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943604/
https://www.ncbi.nlm.nih.gov/pubmed/29743632
http://dx.doi.org/10.1038/s41598-018-25667-3