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A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation
The Ovarian Carcinoma Immunoreactive Antigen domain (OCIAD) - containing proteins OCIAD1/Asrij and OCIAD2, are implicated in several cancers and neurodegenerative diseases. While Asrij has a conserved role in facilitating STAT3 activation for JAK/STAT signaling, the expression and function of OCIAD2...
Autores principales: | Sinha, Saloni, Bheemsetty, Venkata Anudeep, Inamdar, Maneesha S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943604/ https://www.ncbi.nlm.nih.gov/pubmed/29743632 http://dx.doi.org/10.1038/s41598-018-25667-3 |
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