Leukaemic alterations of IKZF1 prime stemness and malignancy programs in human lymphocytes

Somatic cells acquire stem cell-like properties during cancerous transformation; however, mechanisms through which committed cells develop stemness and malignancy remain largely unknown. Here we uncovered upregulated stem cell program in leukaemic lymphoblasts of patients with IKZF1 alterations by a...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhen, Li, Shui-Ping, Li, Ruo-Yan, Zhu, Hua, Liu, Xia, Guo, Xiao-Lin, Mu, Li-Li, Cai, Jie-Jing, Bai, Fan, Chen, Guo-Qiang, Hong, Deng-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943605/
https://www.ncbi.nlm.nih.gov/pubmed/29743561
http://dx.doi.org/10.1038/s41419-018-0600-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943605/
https://www.ncbi.nlm.nih.gov/pubmed/29743561
http://dx.doi.org/10.1038/s41419-018-0600-3

Ejemplares similares