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Central cholinergic system mediates working memory deficit induced by anesthesia/surgery in adult mice

BACKGROUND: Postoperative cognitive dysfunction (POCD) is consistently associated with increased morbidity and mortality, which has become a major concern of patients and caregivers. Although POCD occurs mainly in aged patients, it happens at any age. Previous studies demonstrated that anesthesia/su...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Jiang, Xuliang, Huang, Lili, Tian, Weitian, Chen, Xuemei, Gu, Xiyao, Yu, Weifeng, Tian, Jie, Su, Diansan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943735/
https://www.ncbi.nlm.nih.gov/pubmed/29761010
http://dx.doi.org/10.1002/brb3.957