Membrane translocation of Bruton kinase in multiple myeloma cells is associated with osteoclastogenic phenotype in bone metastatic lesions

Using bone biopsy samples, we examined whether osteolytic cytokine profile is changed in situ in bone samples of metastatic multiple myeloma, and whether this creates an environment of lysis within the bone to which it has spread. This also produces the clinical features of increased circulating pla...

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Detalles Bibliográficos
Autores principales: Li, Li, Tong, Min, Zhao, Yi-ting, He, Yun, Zhou, Hong-yu, Zhang, Guo-fu, Zhang, Yuan-jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943844/
https://www.ncbi.nlm.nih.gov/pubmed/29480835
http://dx.doi.org/10.1097/MD.0000000000009482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943844/
https://www.ncbi.nlm.nih.gov/pubmed/29480835
http://dx.doi.org/10.1097/MD.0000000000009482

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