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Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer

Driver mutation provides fitness advantage to cancer cells, the accumulation of which increases the fitness of cancer cells and accelerates cancer progression. This work seeks to extract patterns accumulated by driver genes (“fitness relationships”) in tumorigenesis. We introduce a network-based met...

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Detalles Bibliográficos
Autores principales: Zhang, Xindong, Gao, Lin, Jia, Songwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943933/
https://www.ncbi.nlm.nih.gov/pubmed/29295608
http://dx.doi.org/10.3390/molecules23010039