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Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer
Driver mutation provides fitness advantage to cancer cells, the accumulation of which increases the fitness of cancer cells and accelerates cancer progression. This work seeks to extract patterns accumulated by driver genes (“fitness relationships”) in tumorigenesis. We introduce a network-based met...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943933/ https://www.ncbi.nlm.nih.gov/pubmed/29295608 http://dx.doi.org/10.3390/molecules23010039 |