Semisynthesis and Biological Evaluation of Oleanolic Acid 3-O-β-d-Glucuronopyranoside Derivatives for Protecting H9c2 Cardiomyoblasts against H(2)O(2)-Induced Injury

A series of novel oleanolic acid 3-O-β-d-glucuronopyranoside derivatives have been designed and synthesized. Biological evaluation has indicated that some of the synthesized compounds exhibit moderate to good activity against H(2)O(2)-induced injury in rat myocardial cells (H9c2). Particularly, deri...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Yu, Sun, Zhonghao, Wang, Wenqian, Shang, Hai, Wang, Baoqi, Deng, Di, Ma, Guoxu, Wu, Haifeng, Zhu, Nailiang, Xu, Xudong, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943939/
https://www.ncbi.nlm.nih.gov/pubmed/29320439
http://dx.doi.org/10.3390/molecules23010044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943939/
https://www.ncbi.nlm.nih.gov/pubmed/29320439
http://dx.doi.org/10.3390/molecules23010044

Ejemplares similares