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Semisynthesis and Biological Evaluation of Oleanolic Acid 3-O-β-d-Glucuronopyranoside Derivatives for Protecting H9c2 Cardiomyoblasts against H(2)O(2)-Induced Injury
A series of novel oleanolic acid 3-O-β-d-glucuronopyranoside derivatives have been designed and synthesized. Biological evaluation has indicated that some of the synthesized compounds exhibit moderate to good activity against H(2)O(2)-induced injury in rat myocardial cells (H9c2). Particularly, deri...
Autores principales: | Tian, Yu, Sun, Zhonghao, Wang, Wenqian, Shang, Hai, Wang, Baoqi, Deng, Di, Ma, Guoxu, Wu, Haifeng, Zhu, Nailiang, Xu, Xudong, Sun, Guibo, Sun, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943939/ https://www.ncbi.nlm.nih.gov/pubmed/29320439 http://dx.doi.org/10.3390/molecules23010044 |
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