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Dopamine and Levodopa Prodrugs for the Treatment of Parkinson’s Disease

Background: Parkinson’s disease is an aggressive and progressive neurodegenerative disorder that depletes dopamine (DA) in the central nervous system. Dopamine replacement therapy, mainly through actual dopamine and its original prodrug l-dopa (LD), faces many challenges such as poor blood brain bar...

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Detalles Bibliográficos
Autores principales: Haddad, Fatma, Sawalha, Maryam, Khawaja, Yahya, Najjar, Anas, Karaman, Rafik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943940/
https://www.ncbi.nlm.nih.gov/pubmed/29295587
http://dx.doi.org/10.3390/molecules23010040