Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects

A series of hybrid of triazoloquinoxaline-chalcone derivatives 7a–k were designed, synthesized, fully characterized, and evaluated for their cytotoxic activity against three target cell lines: human breast adenocarcinoma (MCF-7), human colon carcinoma (HCT-116), and human hepatocellular carcinoma (H...

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Detalles Bibliográficos
Autores principales: Alswah, Mohamed, Bayoumi, Ashraf H., Elgamal, Kamal, Elmorsy, Ahmed, Ihmaid, Saleh, Ahmed, Hany E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943945/
https://www.ncbi.nlm.nih.gov/pubmed/29280968
http://dx.doi.org/10.3390/molecules23010048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943945/
https://www.ncbi.nlm.nih.gov/pubmed/29280968
http://dx.doi.org/10.3390/molecules23010048

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