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Discrimination of Stereoisomers by Their Enantioselective Interactions with Chiral Cholesterol-Containing Membranes

Discrimination between enantiomers is an important subject in medicinal and biological chemistry because they exhibit markedly different bioactivity and toxicity. Although stereoisomers should vary in the mechanistic interactions with chiral targets, their discrimination associated with the mode of...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Hironori, Mizogami, Maki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943951/
https://www.ncbi.nlm.nih.gov/pubmed/29295605
http://dx.doi.org/10.3390/molecules23010049