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Design and Synthesis of Malonamide Derivatives as Antibiotics against Methicillin-Resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to humans. Most existing antimicrobial drugs, including the β-lactam and quinoxiline classes, are not effective against MRSA. In this study, we synthesized 24 derivatives of malonamide, a new class of antibacterial agents and pot...

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Detalles Bibliográficos
Autores principales: Su, Jung-Chen, Huang, Yu-Ting, Chen, Chang-Shi, Chiu, Hao-Chieh, Shiau, Chung-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943958/
https://www.ncbi.nlm.nih.gov/pubmed/29271946
http://dx.doi.org/10.3390/molecules23010027