SPIN1, negatively regulated by miR-148/152, enhances Adriamycin resistance via upregulating drug metabolizing enzymes and transporter in breast cancer

BACKGROUND: Spindlin1 (SPIN1), a protein highly expressed in several human cancers, has been correlated with tumorigenesis and development. Alterations of drug metabolizing enzymes and drug transporters are major determinants of chemoresistance in tumor cells. However, whether the metabolizing enzym...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xu, Wang, Ya-Wen, Gao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944004/
https://www.ncbi.nlm.nih.gov/pubmed/29743122
http://dx.doi.org/10.1186/s13046-018-0748-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944004/
https://www.ncbi.nlm.nih.gov/pubmed/29743122
http://dx.doi.org/10.1186/s13046-018-0748-9

Ejemplares similares