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Muver, a computational framework for accurately calling accumulated mutations

BACKGROUND: Identification of mutations from next-generation sequencing data typically requires a balance between sensitivity and accuracy. This is particularly true of DNA insertions and deletions (indels), that can impart significant phenotypic consequences on cells but are harder to call than sub...

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Detalles Bibliográficos
Autores principales: Burkholder, Adam B., Lujan, Scott A., Lavender, Christopher A., Grimm, Sara A., Kunkel, Thomas A., Fargo, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944071/
https://www.ncbi.nlm.nih.gov/pubmed/29743009
http://dx.doi.org/10.1186/s12864-018-4753-3