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Muver, a computational framework for accurately calling accumulated mutations
BACKGROUND: Identification of mutations from next-generation sequencing data typically requires a balance between sensitivity and accuracy. This is particularly true of DNA insertions and deletions (indels), that can impart significant phenotypic consequences on cells but are harder to call than sub...
Autores principales: | Burkholder, Adam B., Lujan, Scott A., Lavender, Christopher A., Grimm, Sara A., Kunkel, Thomas A., Fargo, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944071/ https://www.ncbi.nlm.nih.gov/pubmed/29743009 http://dx.doi.org/10.1186/s12864-018-4753-3 |
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