Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation

Nodes of Ranvier and associated paranodal and juxtaparanodal domains along myelinated axons are essential for normal function of the peripheral and central nervous systems. Disruption of these domains as well as increases in the reactive carbonyl species methylglyoxal are implicated as a pathophysio...

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Detalles Bibliográficos
Autores principales: Griggs, Ryan B., Yermakov, Leonid M., Drouet, Domenica E., Nguyen, Duc V.M., Susuki, Keiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944142/
https://www.ncbi.nlm.nih.gov/pubmed/29673258
http://dx.doi.org/10.1177/1759091418766175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944142/
https://www.ncbi.nlm.nih.gov/pubmed/29673258
http://dx.doi.org/10.1177/1759091418766175

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