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Tumor Cell–Accelerated Senescence Is Associated With DNA-PKcs Status and Telomere Dysfunction Induced by Radiation

Whether telomere structure integrity is related to radiosensitivity is not well investigated thus far. In this study, we investigated the relation between telomere instability and radiation-induced accelerated senescence. Partial knockdown of DNA-dependent catalytic subunit of protein kinase (DNA-PK...

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Detalles Bibliográficos
Autores principales: Zhang, Miaomiao, Guo, Xiaopeng, Gao, Yue, Lu, Dong, Li, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944147/
https://www.ncbi.nlm.nih.gov/pubmed/29760601
http://dx.doi.org/10.1177/1559325818771527