Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation

Bone resorption and homeostasis is carried out by osteoclasts, whose differentiation and activity are regulated by the RANK/RANKL axis. Our previous studies using a mouse model of joint injury show that joint trauma induces local inflammation followed by bone remodeling. The transcription factor cyc...

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Detalles Bibliográficos
Autores principales: Hu, Zi’ang, Chen, Yilei, Song, Lijiang, Yik, Jasper H. N., Haudenschild, Dominik R., Fan, Shunwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944179/
https://www.ncbi.nlm.nih.gov/pubmed/29773986
http://dx.doi.org/10.3389/fphar.2018.00174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944179/
https://www.ncbi.nlm.nih.gov/pubmed/29773986
http://dx.doi.org/10.3389/fphar.2018.00174

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