Counteraction of Oxidative Stress by Vitamin E Affects Epigenetic Regulation by Increasing Global Methylation and Gene Expression of MLH1 and DNMT1 Dose Dependently in Caco-2 Cells

Obesity- or diabetes-induced oxidative stress is discussed as a major risk factor for DNA damage. Vitamin E and many polyphenols exhibit antioxidative activities with consequences on epigenetic regulation of inflammation and DNA repair. The present study investigated the counteraction of oxidative s...

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Detalles Bibliográficos
Autores principales: Zappe, Katja, Pointner, Angelika, Switzeny, Olivier J., Magnet, Ulrich, Tomeva, Elena, Heller, Jutta, Mare, George, Wagner, Karl-Heinz, Knasmueller, Siegfried, Haslberger, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944233/
https://www.ncbi.nlm.nih.gov/pubmed/29854080
http://dx.doi.org/10.1155/2018/3734250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944233/
https://www.ncbi.nlm.nih.gov/pubmed/29854080
http://dx.doi.org/10.1155/2018/3734250

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