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Exploring local solvation environments of a heme protein using the spectroscopic reporter 4-cyano-l-phenylalanine

The vibrational reporter unnatural amino acid (UAA) 4-cyano-l-phenylalanine (pCNF) was genetically incorporated individually at three sites (5, 36, and 78) in the heme protein Caldanaerobacter subterraneus H-NOX to probe local hydration environments. The UAA pCNF was incorporated site-specifically u...

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Detalles Bibliográficos
Autores principales: Kearney, Caroline, Olenginski, Lukasz T., Hirn, Trexler D., Fowler, Gwendolyn D., Tariq, Daniyal, Brewer, Scott H., Phillips-Piro, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944249/
https://www.ncbi.nlm.nih.gov/pubmed/29780583
http://dx.doi.org/10.1039/c8ra02000k