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Early Growth Response 1 (Egr1) Is a Transcriptional Activator of NOX4 in Oxidative Stress of Diabetic Kidney Disease

BACKGROUND: NADPH oxidase 4 (NOX4) plays a major role in renal oxidative stress of diabetic kidney disease (DKD). NOX4 was significantly increased in Egr1-expressing fibroblasts, but the relationship between Egr1 and NOX4 in DKD is unclear. METHODS: For the evaluation of the potential relationship b...

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Detalles Bibliográficos
Autores principales: Hu, Fang, Xue, Meng, Li, Yang, Jia, Yi-Jie, Zheng, Zong-Ji, Yang, Yan-Lin, Guan, Mei-Ping, Sun, Liao, Xue, Yao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944279/
https://www.ncbi.nlm.nih.gov/pubmed/29854821
http://dx.doi.org/10.1155/2018/3405695