The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress

BACKGROUND: Histone deacetylase (HDAC) inhibitors can attenuate acute kidney injury (AKI)-mediated damage and reduce fibrosis in kidney disease models. The aim of the present study was to investigate the effects of the HDAC inhibitor MS-275 on lipopolysaccharide (LPS)-induced AKI and the associated...

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Detalles Bibliográficos
Autores principales: Zhang, Haiyue, Zhang, Wenbin, Jiao, Fangzhou, Li, Xun, Zhang, Hong, Wang, Luwen, Gong, Zuojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944402/
https://www.ncbi.nlm.nih.gov/pubmed/29704392
http://dx.doi.org/10.12659/MSM.906362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944402/
https://www.ncbi.nlm.nih.gov/pubmed/29704392
http://dx.doi.org/10.12659/MSM.906362

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