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Big Data Toolsets to Pharmacometrics: Application of Machine Learning for Time‐to‐Event Analysis

Additional value can be potentially created by applying big data tools to address pharmacometric problems. The performances of machine learning (ML) methods and the Cox regression model were evaluated based on simulated time‐to‐event data synthesized under various preset scenarios, i.e., with linear...

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Detalles Bibliográficos
Autores principales: Gong, Xiajing, Hu, Meng, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944589/
https://www.ncbi.nlm.nih.gov/pubmed/29536640
http://dx.doi.org/10.1111/cts.12541