An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E

Safe and effective antitoxins to treat and prevent botulism are needed for biodefense. We have developed recombinant antibody-based therapeutics for botulinum neurotoxin (BoNT) serotypes A, B, and E. The mechanism of action of this antitoxin requires that three mAbs bind one toxin molecule to achiev...

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Detalles Bibliográficos
Autores principales: Li, Mingxiang, Lee, Dennis, Obi, Chidi R., Freeberg, Joel K., Farr-Jones, Shauna, Tomic, Milan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944936/
https://www.ncbi.nlm.nih.gov/pubmed/29746518
http://dx.doi.org/10.1371/journal.pone.0197011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944936/
https://www.ncbi.nlm.nih.gov/pubmed/29746518
http://dx.doi.org/10.1371/journal.pone.0197011

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