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An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E
Safe and effective antitoxins to treat and prevent botulism are needed for biodefense. We have developed recombinant antibody-based therapeutics for botulinum neurotoxin (BoNT) serotypes A, B, and E. The mechanism of action of this antitoxin requires that three mAbs bind one toxin molecule to achiev...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944936/ https://www.ncbi.nlm.nih.gov/pubmed/29746518 http://dx.doi.org/10.1371/journal.pone.0197011 |