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Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas
Drug resistant tuberculosis is increasing world-wide. Resistance against isoniazid (INH), rifampicin (RIF), or both (multi-drug resistant TB, MDR-TB) is of particular concern, since INH and RIF form part of the standard regimen for TB disease. While it is known that suboptimal treatment can lead to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944939/ https://www.ncbi.nlm.nih.gov/pubmed/29746491 http://dx.doi.org/10.1371/journal.pone.0196322 |