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CUL5 is required for thalidomide-dependent inhibition of cellular proliferation

Angiogenesis is essential for cancer metastasis, thus the discovery and characterization of molecules that inhibit this process is important. Thalidomide is a teratogenic drug which is known to inhibit angiogenesis and effectively inhibit cancer metastasis, yet the specific cellular targets for its...

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Detalles Bibliográficos
Autores principales: Kunkler, Bryan, Salamango, Daniel, DeBruine, Zachary J., Ploch, Caitlin, Dean, Shirley, Grossens, David, Hledin, Michael P., Marquez, Gabriel A., Madden, Julie, Schnell, Abigayle, Short, Michael, Burnatowska-Hledin, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944951/
https://www.ncbi.nlm.nih.gov/pubmed/29746508
http://dx.doi.org/10.1371/journal.pone.0196760