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The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation

To subvert host defenses, Mycobacterium tuberculosis (Mtb) avoids being delivered to degradative phagolysosomes in macrophages by arresting the normal host process of phagosome maturation. Phagosome maturation arrest by Mtb involves multiple effectors and much remains unknown about this important as...

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Detalles Bibliográficos
Autores principales: Zulauf, Katelyn E., Sullivan, Jonathan Tabb, Braunstein, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945054/
https://www.ncbi.nlm.nih.gov/pubmed/29709019
http://dx.doi.org/10.1371/journal.ppat.1007011