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HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition

Immune response against human cytomegalovirus (HCMV) includes a set of persistent cytotoxic NK and CD8 T cells devoted to eliminate infected cells and to prevent reactivation. CD8 T cells against HCMV antigens (pp65, IE1) presented by HLA class-I molecules are well characterized and they associate w...

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Detalles Bibliográficos
Autores principales: Jouand, Nicolas, Bressollette-Bodin, Céline, Gérard, Nathalie, Giral, Magali, Guérif, Pierrick, Rodallec, Audrey, Oger, Romain, Parrot, Tiphaine, Allard, Mathilde, Cesbron-Gautier, Anne, Gervois, Nadine, Charreau, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945056/
https://www.ncbi.nlm.nih.gov/pubmed/29709038
http://dx.doi.org/10.1371/journal.ppat.1007041