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Mib1 prevents Notch Cis-inhibition to defer differentiation and preserve neuroepithelial integrity during neural delamination

The vertebrate neuroepithelium is composed of elongated progenitors whose reciprocal attachments ensure the continuity of the ventricular wall. As progenitors commit to differentiation, they translocate their nucleus basally and eventually withdraw their apical endfoot from the ventricular surface....

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Detalles Bibliográficos
Autores principales: Baek, Chooyoung, Freem, Lucy, Goïame, Rosette, Sang, Helen, Morin, Xavier, Tozer, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945229/
https://www.ncbi.nlm.nih.gov/pubmed/29708962
http://dx.doi.org/10.1371/journal.pbio.2004162