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Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma

INTRODUCTION: The glioblastoma (GBM) immune microenvironment is highly suppressive as it targets and hinders multiple components of the immune system. Checkpoint blockade (CB) is being evaluated for GBM patients. However, biomarker analyses suggest that CB monotherapy may be effective only in a smal...

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Detalles Bibliográficos
Autores principales: Garzon-Muvdi, Tomas, Theodros, Debebe, Luksik, Andrew S., Maxwell, Russell, Kim, Eileen, Jackson, Christopher M., Belcaid, Zineb, Ganguly, Sudipto, Tyler, Betty, Brem, Henry, Pardoll, Drew M., Lim, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945499/
https://www.ncbi.nlm.nih.gov/pubmed/29755681
http://dx.doi.org/10.18632/oncotarget.25061