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Prognostic value of LINE-1 methylation level in 321 patients with primary liver cancer including hepatocellular carcinoma and intrahepatic cholangiocarcinoma

BACKGROUND: The methylation level of long interspersed nucleotide element-1 (LINE-1) is a good surrogate marker of the global DNA methylation level. The relationship between LINE-1 methylation level and prognosis in primary liver cancer (PLC) patients remains unclear. RESULTS: LINE-1 methylation lev...

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Detalles Bibliográficos
Autores principales: Miyata, Tatsunori, Yamashita, Yo-Ichi, Baba, Yoshifumi, Harada, Kazuto, Yamao, Takanobu, Umezaki, Naoki, Tsukamoto, Masayo, Kitano, Yuki, Yamamura, Kensuke, Arima, Kota, Nakagawa, Shigeki, Okabe, Hirohisa, Imai, Katsunori, Hashimoto, Daisuke, Chikamoto, Akira, Shimokawa, Mototsugu, Baba, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945516/
https://www.ncbi.nlm.nih.gov/pubmed/29755690
http://dx.doi.org/10.18632/oncotarget.25124