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COP9 signalosome subunit 5 regulates cancer metastasis by deubiquitinating SNAIL

Cancer metastasis is a major cause of mortality in cancer patients. The transcription factor SNAIL plays an important role in cancer metastasis and progression, and its expression is tightly regulated by the ubiquitin-proteasome system through the balance between ubiquitin ligases and deubiquitinati...

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Detalles Bibliográficos
Autores principales: Watanabe, Kensuke, Yokoyama, Satoru, Kaneto, Naoki, Hori, Takashi, Iwakami, Yusuke, Kato, Shinichiro, Hayakawa, Yoshihiro, Sakurai, Hiroaki, Fukuoka, Junya, Saiki, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945527/
https://www.ncbi.nlm.nih.gov/pubmed/29755680
http://dx.doi.org/10.18632/oncotarget.25060