Evaluation of the primitive fraction by functional in vitro assays at the RNA and DNA level represents a novel tool for complementing molecular monitoring in chronic myeloid leukemia

Quantification of BCR-ABL1 mRNA levels in peripheral blood of chronic myeloid leukemia patients is a strong indicator of response to tyrosine-kinase inhibitors (TKI) treatment. However, additional prognostic markers are needed in order to better classify patients. The hypothesis of leukemic stem cel...

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Detalles Bibliográficos
Autores principales: Ruiz, María Sol, Sanchez, María Belén, Gutiérrez, Leandro, Koile, Daniel, Yankilevich, Patricio, Mosqueira, Celeste, Cranco, Santiago, Custidiano, María del Rosario, Freitas, Josefina, Foncuberta, Cecilia, Moiraghi, Beatriz, Pavlovsky, Carolina, Pérez, Mariel Ana, Ventriglia, Verónica, Ávalos, Julio Sanchez, Mordoh, José, Larripa, Irene, Bianchini, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945542/
https://www.ncbi.nlm.nih.gov/pubmed/29755649
http://dx.doi.org/10.18632/oncotarget.24749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945542/
https://www.ncbi.nlm.nih.gov/pubmed/29755649
http://dx.doi.org/10.18632/oncotarget.24749

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