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Beyond molecular tumor heterogeneity: protein synthesis takes control

One of the daunting challenges facing modern medicine lies in the understanding and treatment of tumor heterogeneity. Most tumors show intra-tumor heterogeneity at both genomic and proteomic levels, with marked impacts on the responses of therapeutic targets. Therapeutic target-related gene expressi...

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Detalles Bibliográficos
Autores principales: Ramon y Cajal, Santiago, Castellvi, Josep, Hümmer, Stefan, Peg, Vicente, Pelletier, Jerry, Sonenberg, Nahum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945578/
https://www.ncbi.nlm.nih.gov/pubmed/29463861
http://dx.doi.org/10.1038/s41388-018-0152-0