The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia

Chromosomal translocations involving the MLL1 gene characterize a poor prognosis subset of acute myeloid leukemia (AML), referred to as 11q23-AML. Transcription of the HOXA9 and HOXA10 genes is enhanced in hematopoietic stem and progenitor cells in these leukemias. We previously found the ARIH2 gene...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Bei, Ling, Shah, Chirag A., Huang, Weiqi, Platanias, Leonidas C., Eklund, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945580/
https://www.ncbi.nlm.nih.gov/pubmed/29459712
http://dx.doi.org/10.1038/s41388-018-0131-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945580/
https://www.ncbi.nlm.nih.gov/pubmed/29459712
http://dx.doi.org/10.1038/s41388-018-0131-5

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