Structural basis for cofilin binding and actin filament disassembly

Actin depolymerizing factor (ADF) and cofilin accelerate actin dynamics by severing and disassembling actin filaments. Here, we present the 3.8 Å resolution cryo-EM structure of cofilactin (cofilin-decorated actin filament). The actin subunit structure of cofilactin (C-form) is distinct from those o...

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Detalles Bibliográficos
Autores principales: Tanaka, Kotaro, Takeda, Shuichi, Mitsuoka, Kaoru, Oda, Toshiro, Kimura-Sakiyama, Chieko, Maéda, Yuichiro, Narita, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945598/
https://www.ncbi.nlm.nih.gov/pubmed/29749375
http://dx.doi.org/10.1038/s41467-018-04290-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945598/
https://www.ncbi.nlm.nih.gov/pubmed/29749375
http://dx.doi.org/10.1038/s41467-018-04290-w

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