Simulated microgravity induces a cellular regression of the mature phenotype in human primary osteoblasts

Decreased mechanical loading on bones, such as prolonged bed rest and microgravity during space flights, leads to the development of an osteoporotic-like phenotype. Although osteoblast hypo-functionality is reported to be involved in the progression of bone pathological conditions, the cellular mech...

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Detalles Bibliográficos
Autores principales: Gioia, Magda, Michaletti, Anna, Scimeca, Manuel, Marini, Mario, Tarantino, Umberto, Zolla, Lello, Coletta, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945613/
https://www.ncbi.nlm.nih.gov/pubmed/29760957
http://dx.doi.org/10.1038/s41420-018-0055-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945613/
https://www.ncbi.nlm.nih.gov/pubmed/29760957
http://dx.doi.org/10.1038/s41420-018-0055-4

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