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Simulated microgravity induces a cellular regression of the mature phenotype in human primary osteoblasts
Decreased mechanical loading on bones, such as prolonged bed rest and microgravity during space flights, leads to the development of an osteoporotic-like phenotype. Although osteoblast hypo-functionality is reported to be involved in the progression of bone pathological conditions, the cellular mech...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945613/ https://www.ncbi.nlm.nih.gov/pubmed/29760957 http://dx.doi.org/10.1038/s41420-018-0055-4 |