The effects of mutational processes and selection on driver mutations across cancer types

Epidemiological evidence has long associated environmental mutagens with increased cancer risk. However, links between specific mutation-causing processes and the acquisition of individual driver mutations have remained obscure. Here we have used public cancer sequencing data from 11,336 cancers of...

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Detalles Bibliográficos
Autores principales: Temko, Daniel, Tomlinson, Ian P. M., Severini, Simone, Schuster-Böckler, Benjamin, Graham, Trevor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945620/
https://www.ncbi.nlm.nih.gov/pubmed/29748584
http://dx.doi.org/10.1038/s41467-018-04208-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945620/
https://www.ncbi.nlm.nih.gov/pubmed/29748584
http://dx.doi.org/10.1038/s41467-018-04208-6

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