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Humanizing Miniature Hearts through 4-Flow Cannulation Perfusion Decellularization and Recellularization

Despite improvements in pre-clinical drug testing models, predictability of clinical outcomes continues to be inadequate and costly due to poor evidence of drug metabolism. Humanized miniature organs integrating decellularized rodent organs with tissue specific cells are translational models that ca...

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Detalles Bibliográficos
Autores principales: Nguyen, Duong T., O’Hara, Matthew, Graneli, Cecilia, Hicks, Ryan, Miliotis, Tasso, Nyström, Ann-Christin, Hansson, Sara, Davidsson, Pia, Gan, Li-Ming, Magnone, Maria Chiara, Althage, Magnus, Heydarkhan-Hagvall, Sepideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945628/
https://www.ncbi.nlm.nih.gov/pubmed/29748585
http://dx.doi.org/10.1038/s41598-018-25883-x