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Prion protein is essential for the RE1 silencing transcription factor (REST)-dependent developmental switch in synaptic NMDA receptors

It is important that the correct amounts of GluN2 subunits are maintained, as they determine NMDAR functional properties, which are crucial to neuronal communication, synaptogenesis and cognitive function. The transcriptional repressor RE1 silencing transcription factor (REST) is critical for the po...

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Detalles Bibliográficos
Autores principales: Song, Zhiqi, Yang, Wei, Cheng, Guangyu, Zhou, Xiangmei, Yang, Lifeng, Zhao, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945644/
https://www.ncbi.nlm.nih.gov/pubmed/29748616
http://dx.doi.org/10.1038/s41419-018-0576-z