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Eukaryotic Translation Initiation Factor 4 Gamma 1 (eIF4G1) is upregulated during Prostate cancer progression and modulates cell growth and metastasis

eIF4G1, a critical component of the eIF4F complex, is required for cap-dependent mRNA translation, a process necessary for tumor growth and survival. However, the role of eIF4G1 has not been evaluated in Prostate Cancer (PCa). We observed an increased eIF4G1 protein levels in PCa tissues as compared...

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Detalles Bibliográficos
Autores principales: Jaiswal, Praveen Kumar, Koul, Sweaty, Shanmugam, Prakash S. T., Koul, Hari K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945649/
https://www.ncbi.nlm.nih.gov/pubmed/29748619
http://dx.doi.org/10.1038/s41598-018-25798-7