Effect of Bmi1 over-expression on gene expression in adult and embryonic murine neural stem cells

The ability of isolated neural stem cells (NSCs) to proliferate as neurospheres is indicative of their competence as stem cells, and depends critically on the polycomb group (PcG) member Bmi1: knockdown of Bmi1 results in defective proliferation and self-renewal of isolated NSCs, whereas overexpress...

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Detalles Bibliográficos
Autores principales: Ganapathi, Mythily, Boles, Nathan C., Charniga, Carol, Lotz, Steven, Campbell, Melissa, Temple, Sally, Morse, Randall H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945652/
https://www.ncbi.nlm.nih.gov/pubmed/29749381
http://dx.doi.org/10.1038/s41598-018-25921-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945652/
https://www.ncbi.nlm.nih.gov/pubmed/29749381
http://dx.doi.org/10.1038/s41598-018-25921-8

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