Reversible glycosidic switch for secure delivery of molecular nanocargos

Therapeutic drugs can leak from nanocarriers before reaching their cellular targets. Here we describe the concept of a chemical switch which responds to environmental conditions to alternate between a lipid-soluble state for efficient cargo loading and a water-soluble state for stable retention of c...

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Detalles Bibliográficos
Autores principales: Burnouf, Pierre-Alain, Leu, Yu-Lin, Su, Yu-Cheng, Wu, Kenneth, Lin, Wei-Chi, Roffler, Steve R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945669/
https://www.ncbi.nlm.nih.gov/pubmed/29748577
http://dx.doi.org/10.1038/s41467-018-04225-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945669/
https://www.ncbi.nlm.nih.gov/pubmed/29748577
http://dx.doi.org/10.1038/s41467-018-04225-5

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