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Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies

Nucleolin arises as a relevant target for cancer therapy, as it is overexpressed at the surface of cancer and angiogenic endothelial cells thus enabling a dual cellular targeting strategy. Immunotherapeutic strategies, albeit of proven therapeutic relevance, have been scarcely explored against this...

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Detalles Bibliográficos
Autores principales: Romano, Sofia, Moura, Vera, Simões, Sérgio, Moreira, João Nuno, Gonçalves, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945777/
https://www.ncbi.nlm.nih.gov/pubmed/29748553
http://dx.doi.org/10.1038/s41598-018-25816-8