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Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies
Nucleolin arises as a relevant target for cancer therapy, as it is overexpressed at the surface of cancer and angiogenic endothelial cells thus enabling a dual cellular targeting strategy. Immunotherapeutic strategies, albeit of proven therapeutic relevance, have been scarcely explored against this...
Autores principales: | Romano, Sofia, Moura, Vera, Simões, Sérgio, Moreira, João Nuno, Gonçalves, João |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945777/ https://www.ncbi.nlm.nih.gov/pubmed/29748553 http://dx.doi.org/10.1038/s41598-018-25816-8 |
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