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CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target

CARF (Collaborator of ARF)/CDKN2AIP was discovered as a novel ARF-binding protein. It has been established as an essential cell survival, p53-, and cell proliferation-regulatory protein. Although a moderate upregulation of CARF caused growth arrest and senescence, its excessively enriched levels wer...

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Detalles Bibliográficos
Autores principales: Kalra, Rajkumar S., Chaudhary, Anupama, Yoon, A-Rum, Bhargava, Priyanshu, Omar, Amr, Garg, Sukant, Yun, Chae-Ok, Kaul, Sunil C., Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945778/
https://www.ncbi.nlm.nih.gov/pubmed/29748568
http://dx.doi.org/10.1038/s41389-018-0048-4