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Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies

The innate immune response in the central nervous system (CNS) is implicated as both beneficial and detrimental to health. Integral to this process are microglia, the resident immune cells of the CNS. Microglia express a wide variety of pattern-recognition receptors, such as Toll-like receptors, tha...

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Detalles Bibliográficos
Autores principales: Caplan, Ian F., Maguire-Zeiss, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945810/
https://www.ncbi.nlm.nih.gov/pubmed/29780321
http://dx.doi.org/10.3389/fphar.2018.00417